Tumor-infiltrating immune cells in Head and Neck cancer
Our overall objective is to extend our understanding on the role of tumor-infiltrating leukocytes in oropharyngeal (OPC) and nasopharyngeal (NPC) cancer, frequently associated to HPV and EBV infections, in order to identify novel strategies for enhancing anti-tumor responses. We also aim at establishing a 3D organoid platform of OPC to enable functional studies of cellular anti-tumor immunity and preclinical assessment of efficacy for immune-oncology therapeutics.
Current projects include:
Immune Profiling of Head and Neck cancers
In vitro 3D cell systems of oropharyngeal cancer