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Immunotechnology

Faculty of Engineering, LTH

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Theses

2020

Ljungars, Anne. Phenotypic antibody discovery and mining of complex antibody libraries. (Abstract)

2019

Lindberg, Tim. Mechanistic Toxicology - Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization. (Abstract)

2018

Brofelth, Mattias. Technological advancements in affinity proteomics : From planar antibody microarrays towards a solution-based platform. (Abstract)

Siino, Valentina. Phosphoproteomics to tackle brain disorders: Insight into the murine brain phosphoproteome. (Abstract)

2017

Liljedahl, Leena. Exploring the diabetic kidney proteome. A junction of tissue and serum. (Abstract)

Sjöholm, Kristoffer. A holistic approach to host-pathogen interactions: Detecting the large to unravel the small. (Abstract)

Skoog, Petter. Molecular portraits of cancer: Discovery of biomarker signatures using affinity proteomics. (Abstract)

Kurbasic, Emila. Landscaping the cell surface proteome of breast cancer: Following pathways through organelles to the plasma. (Abstract)

Forreryd, Andy. GARD-Genomic allergen rapid detection. From biomarker discovery towards a state-of-the-art testing platform for chemical sensitizers. (Abstract)
  

2016

Kuci Emruli, Venera. A molecular dissection of mantle cell lymphoma. From gene expression analysis to functional evaluation of selected targets. (Abstract)

Teleman, Johan. Quantitative analysis of mass spectrometry proteomics data - software for improved life science. (Abstract)

Delfani, Payam. Biomarker discovery in autoimmune diseases using antibody microarrays: Targeting systemic lupus erythematosus. (Abstract)

Kilsgård, Ola. Proteomic profiling of bacterial host adaptation: Racing the Red Queen. (Abstract)
   

2015

Kirik, Ufuk. Development of computational methods for cancer research: Strategies for closing the feedback loop in omics workflows. (Abstract)

Rydnert, Frida. Circulating human basophils and dendritic cell subsets. Aspects of antigen recognition and presentation in type I allergic immune responses. (Abstract)

Säll, Anna. Recombinant antibodies – Tools for building proteomic platforms (Abstract)
    

2014

Petersson, Linn. Tailoring of antibody arrays - Technical advances towards global proteome analysis. (Abstract)

Nordström, Lena. SOX11 in mantle cell lymphoma - Novel tools for diagnostic, prognostic and functional investigations. (Abstract)

Pauly, Frida. Biomarker discovery in cancer using affinity proteomics - Studies of B-cell lymphomas and breast cancer. (Abstract)

Sandin, Marianne. Quality control for high-throughput quantitative proteomics - Harnessing the potential of label-free LC-MS. (Abstract)
   

2013

Sernbo, Sandra. Functional studies of SOX11 and T-STAR. Translation of tumor-associated genes into clinical and biological insight. (Abstract)

Antberg, Linn. A proteomic dissecton of breast cancer. Via cells and organelles to pathways. (Abstract)

Broos, Sissela. Specific targeting of antigen-presenting cells for immunotherapy. (Abstract)

Nordström, Malin. Biomarker discovery in cancer and autoimmunity using an affinity proteomics platform - a tool for personalized medicine. (Abstract)

Cifani, Paolo. Building a map of the breast cancer proteome - Strategies to increase coverage. (Abstract)

Johansson, Henrik. GARD - Genomic Allergen Rapid Detection. A testing strategy for assessment of chemical sensitizers. (Abstract)

Levin, Mattias. Human IgE - What we can learn from repertoire studies and how we can use them as tools. (Abstract)

Gerdtsson, Anna S. Advances and applications of antibody arrays - Proteomic profiling of pancreatic disease. (Abstract)
  

2012

Carlsson, Fredrika. Antibody development - Examples from viral and proteomic studies. (Abstract)

Olsson, Niclas. Global Proteome Survey - Transforming antibody-based affinity proteomics into a global discovery platform. (Abstract)

von Schantz, Laura. Engineering protein-carbohydrate interactions - lessons from natural and evolved carbohydrate binding modules. (Abstract)
  

2010

Dexlin Mellby, Linda. Design of antibody microarrays for global profiling of
membrane proteins and soluble proteins. (Abstract)

Carlsson, Anders. Molecular serum portraits - A step towards personalized medicine. (Abstract)

Gustavsson, Elin. SOX11 as a cancer biomarker - Expression and regulatory studies in B-cell lymphoma and ovarian cancer. (Abstract)
    

2009

Gustafsson, Erika. Molecular evolution of a C5aR antagonist against inflammatory disease. (Abstract)

Lundberg, Kristina. Subsets of human dendritic cells and their role in allergy. (Abstract)

Andréasson, Ulrika. Transcriptional analysis of cell-sorted B-cell lymphomas from high-throughput to focused identification of molecular targets. (Abstract)

2008

Persson, Jonas. Selection and design in antibody phage display. (Abstract)
    

2007

Cicortas Gunnarsson, Lavinia. Novel binding specificities engineered into the scaffold of a carbohydrate binding module. (Abstract)

Waldemarson, Sofia. Profiling the cancer proteome. Studies on breast, ovarian and prostate cancer. (Abstract)

Persson, Helena. Generation and evolution of human antibody repertoires. (Abstract)

Wåhlander, Åsa. Chemical labelling methods for gel free based proteomics. (Abstract)

Larsson, Kristina. Dendritic cells in allergy. In vitro models for studies of the human immune response. (Abstract)

Jansson, Maria. Membrane protein proteomics - Novel method for membrane protein identification and quantification. (Abstract)
     

2006

Fransson, Johan. Functionally-associated target antigens in cancer. Defined by human antibodies and small interfering RNAs. (Abstract)

Ingvarsson, Johan. Design of recombinant antibody microarrays for global proteome analysis. (Abstract)
   

2005

Lindstedt, Malin. Human dendritic cells and the regulation of allergic immune responses. (Abstract)

Högerkorp, Carl-Magnus. Genomic and molecular aspects of mature human B cells. (Abstract)

Steinhauer, Cornelia. Protein microarrays based on single framework recombinant antibody fragments (SINFABS) - catcher and carrier - a crucial combination. (Abstract)
   

2004

Dahm, Åsa. Zeolites as tools in immunology and cellbiology. (licenciate thesis)

Ek, Sara. Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets. (Abstract)

Karlsson, Fredrik. The biology of filamentous phage infection ­ implications for display technology (Abstract)
   

2002

Johansson-Lindbom, Bengt. Regulatory properties of dendritic cells and B cells in adaptive immunity. (Abstract)

Lantto, Johan. Antibody evolution and repertoire development. (Abstract)

Ellmark, Peter. The CD40 receptor - target, tool and technology. (Abstract)
    

2001

Åkesson, Anna. Mechanisms of antigen-specific IgE-secretion in vitro. (licenciate thesis)
    

2000

Nilsson, Nina. In vivo and in vitro evolution of molecular mechanisms. Importance in B cell development and phage display. (Abstract)

Ottosson, Camilla. In vitro evolution by the FIND system and selection of novel phage antibodies. (licenciate thesis)

Strandh, Magnus. Insights into weak affinity antibody-antigen interactions. Studies using affinity chromatography and optical biosensors. (Abstract)

Jirholt, Pernilla. Generation and evolution of human antibody fragments - The CDR shuffling approach. (Abstract)
    

1998

Ingvarsson, Sigurdur. Signalling mechanisms in B cell differentitation. Studies on specific human immune response in vitro. (Abstract)

Dahlenborg, Katarina. Cellular and molecular aspects of the germinal centre reaction. (Abstract)

Andersson, Eva. Studies of T- and B-cells for the generation of human antigen specific antibodies. (Abstract)
   

1996

Simonsson Lagerkvist, Ann Catrin. In vitro generation and selection of antigen-specific antibodies. (Abstract)

Furebring, Christina. Expression of Ig genes. Regulation of transcription and production of human antibodies. (Abstract)

Malmborg, Ann-Christin. Molecular recognition in antibody engineering. Studies on recombinant and phage displayed antibodies. (Abstract)

Wallén-Öhman, Marie. MHC class I-induced apoptosis in hematopoietic cells. (Abstract)
     

1995

Dueñas, Marta. Phage display and bacterial expression of antibody fragments. (Abstract)

Eriksson, Christina. The SCID mouse. A tool for generation of human monoclonal antibodies? (Abstract)

Ifversen, Peter. Human antibody technology. An evaluation of the SCID-hu-PBL model. (Abstract)
   

1994

Chin, Li-te. Site-directed in vitro immunization. A model of sequential antigen-specific activation of human B cells. (Abstract)

1993

Kristensson, Karin. T cell mediated effects on in vitro B cell responses. (Abstract)
   

1992

Ohlin, Mats. Human Monoclonal Antibody Technology. A tool to investigate human antibody repertoires. (Abstract)
   

1990

Danielsson, Lena. Human Monoclonal Antibodies. In vitro Immunization and Cloning of DNA Encoding Variable Regions. (Abstract)

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