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Immunotechnology

Faculty of Engineering, LTH

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Molecular interactions: surface plasmon resonance

Surface plasmon resonance

Surface plasmon resonance (SPR) is an optical-based, label-free detection technology for real-time monitoring of binding interactions between two or more molecules.  A wide range of molecules can be studied, from ions and fragments to proteins and viruses. This innovative technology is capable of providing biophysical data such as affinity, kinetics and thermodynamics, in addition to answering basic questions of binding specificity and concentration. We offer services with the MASS-16 instrument. If you wish to learn more about the technology than described below, please, visit the instrument homepage.

MASS-16 instrument

MASS-16™  is short for Molecular Affinity Screening System. This is a biosensor that allows you to study the interaction between two biomolecules in real time. The MASS-16 equipment uses a detection system that is based on surface plasmon resonance (SPR), and you measure the interaction in real time without the need for any labeling of reagents.

  • high-throughput kinetic analysis, 96 and 384 well based platform
  • eight dual sensor flow cells enable to analyse 8 different samples simultaneously
  • easy software to build the assay method and analyse the data.
  • integrated with a robotic arm and a stacker for up to 12 plates